Egg Donation

What is egg donation?

Egg donation is the process by which a person or couple receives donated eggs to enable conception through assisted reproductive technology.

Who is egg donation right for?

Egg donation is a option for any prospective parents who do not produce egg cells or who have genetic concerns about a pregnancy. This includes families with:

  • prospective parents who only produce sperm and will use a gestational carrier (also called a surrogate)

  • a prospective parent with a uterus to carry a pregnancy, but who has reduced ovarian function

How much does egg donation cost?

The cost of donor eggs varies greatly.

Some people prefer to find a known donor, who can be a friend, a family member, or someone they have met for the sole purpose of working with them as a donor. Working with a known donor can reduce costs, and some families like having a personal relationship with their egg donor.

Another option is to work with an egg donor program to secure cryopreserved eggs that you can utilize for your family-building process. An egg donor program is more expensive because they’ve worked to locate donors who are most likely to have viable eggs, but some families prefer to have an unknown donor.

Please contact us to schedule a fertility health consult and discuss donor egg costs for your specific needs.

How can partners be involved in the process?

At Main Line Fertility, we are eager to include partners at every step of the process. Here are a few ways partners can be integral to your conception journey:

As you are selecting an egg donor, work together to decide which characteristics or qualities you may look for in a donor. There are several mobile apps that can be used for picking a baby name; you AND your partner enter names you each love and then the app presents you with the names you both selected. These apps can be used for selecting egg donors! You can both look through a library of donors or think through potential donors in your life, list the names or donor numbers in the app, then see which donors you both selected.

Partners can also do a lot of the logistical and emotional labor involved in a conception process. They can call to book appointments, pick up prescriptions, ensure sperm is transported safely, and more! Fertility processes go well when both partners feel equally engaged and invested in the process. Don’t be afraid to ask for help from your partner, to offer help to your partner, and to ask for what you need.

Does Main Line Fertility have an in-house egg donor bank?

Yes! Main Line Fertility offers one of the country’s largest and most experienced egg donation programs.

Our exclusive in-house no wait donor egg database enables us to provide our patients with access to over two thousand high quality eggs in a time frame that fits their busy schedules. Main Line Fertility patients have the option of choosing a fresh donor egg cycle or a frozen donor egg cycle. In addition to meeting all FDA compliance standards, our egg donors complete a thorough medical, psychological and genetic screening process by our physicians. For unknown egg donors, we maintain strict confidentiality of the donor’s and the recipient’s identity. The egg recipient will have access to all of the available donor medical history.

Should we use known or unknown donors?

There are benefits and drawbacks to both known and unknown donor options. To start, let’s define each:

Known Donor: A donor whose identity is known to you. A known donor is often someone you know, such as a friend or acquaintance, or can be someone you met for the express purpose of egg donation.

Unknown Donor: A donor who went through an intermediary, whose identity is intended to be unknown to you. You may be familiar with the phrase “anonymous donor,” but because of readily available genetic testing, the concept of anyone being truly “anonymous” is no longer an option.

Now, what are the benefits and drawbacks of each type of donor? Let’s look!

Known Donor

Benefits:

  • Some families want the option of having a donor who is committing to some level of involvement in their lives (or the lives of their children). This option is only available if you use a known donor.

  • Should any questions about genetic diversity, allergies, developmental milestones, etc. come up, some families like the option of asking their donor for more information about those medical and/or developmental topics.

  • Some couples choose to have a relative donate egg for their pregnancy, such as the sister of the partner who is not carrying the pregnancy. This allows for a genetic connection between the non-carrying partner and the pregnancy.

Drawbacks:

  • The legal connection between a known donor and a pregnancy can be complicated, depending on where you live. In some cases, known donors will have to go to court (perhaps even multiple times) in order to sever their legal connection to the pregnancy and ensuing baby. These court dates can be expensive.

  • There are times when donors have a change of heart, either about donating or about the type of relationship they would like to have with the pregnancy and ensuing baby. This can make for complicated, even legally messy situations.

  • In some cases, the relatives of the known donor may attempt to establish social or even legal connections to the pregnancy and/or ensuing baby.

Unknown Donor

Benefits:

  • Some families want the option of having a donor who has committed to no level of involvement in their lives (or the lives of their children). This guarantee is only available if you use an unknown donor.

  • If working with a cryobank, extensive testing is done on every donor with an emphasis on sperm quality/quantity, background examination of mental health conditions, and three generations of medical histories are examined for each donor.

  • If working with a cryobank, donors have already severed legal ties with their samples, so there is no concern about legal challenges by donors.

Drawbacks:

  • There are limited options for communicating with donors about medical questions or concerns. Cryobanks may be able to act as an intermediary, but the donor will be able to decide whether they choose to communicate and their anonymity will be prioritized throughout the process.

  • Some donor-conceived children believe that every person has the right to know the person who contributed the sperm that created them, and that type of relationship isn’t possible with an unknown donor.

Sperm Donation

What is sperm donation?

Sperm donation is the process in which a person or couple receives donor sperm to enable conception through assisted reproductive technology. Sperm donors can be unknown (an “anonymous” donor) or known (a relative or friend).

Who is sperm donation right for?

Donor sperm might be right for you if neither you nor your partner(s) produce sperm.

If you have undergone hormone replacement therapy and have an absence of sperm in the semen (Azoospermia), low sperm count, poor sperm motility and/or abnormal sperm morphology as a result, donor sperm can be a great option for building your family.

How much does buying sperm cost?

The cost for a sample of sperm is on average $400 to $800, which contains 3-6 vials of sperm.

How many samples should we expect to need?

The number of samples your family will need depends on the fertility process you are choosing and the number of pregnancies you will be attempting. Each sample comes with 3-6 vials of sperm, which can each be used for one fertility cycle.

For IVF, it is possible that one sperm vial can be used to create multiple embryos that can be frozen and saved for multiple cycles and multiple pregnancies.

For IUI or INVOCELL, you will need a separate vial for each cycle.

How can partners be involved in the process?

At Main Line Fertility, we are eager to include partners at every step of the process. Here are a few ways partners can be integral to your conception journey:

As you are selecting a sperm donor, work together to decide which characteristics or qualities you may look for in a donor. There are several mobile apps that can be used for picking a baby name; you AND your partner enter names you each love and then the app presents you with the names you both selected. These apps can be used for selecting sperm donors! You can both look through a cryobank library of donors or think through potential donors in your life, list the names or donor numbers in the app, then see which donors you both selected.

Partners can also do a lot of the logistical and emotional labor involved in a conception process. They can call to book appointments, pick up prescriptions, ensure sperm is transported safely, and more! Fertility processes go well when both partners feel equally engaged and invested in the process. Don’t be afraid to ask for help from your partner, to offer help to your partner, and to ask for what you need (regardless of whether you’re the person conceiving or not).

Should we use fresh or frozen sperm?

For in vitro fertilization (IVF) and INVOCELL, pregnancy outcomes for fresh and frozen sperm are similar. Which you will use will depend on your proximity to the donor.

For Intravaginal, Intracervical, or Intrauterine Insemination , there are benefits and drawbacks to both fresh and frozen options. Let’s take a look!

Fresh Sperm

If you’re working with a known donor, such as a friend or someone you have met for the express purpose of utilizing them as a donor, you may be able to use their sperm without it being frozen first.

Benefits:

  • Live, fresh sperm can substantially more “potent” than frozen sperm

Drawbacks:

  • Often, individuals and couples working with known donors aren’t aware of the added benefits of additional screening that can help ensure that their donor is producing samples that are high quality. Many of our patients attempt insemination without realizing that their known donor doesn’t have the sperm quality and quantity necessary to achieve a pregnancy.

  • Fresh sperm dies quickly! If utilizing fresh sperm, insemination must happen quickly.

  • Fresh sperm has filler material (often called semen) that isn’t appropriate for an IUI. Sperm must be “washed” in order to remove this excess material before it can be used in IUI. So fresh sperm can only be used for Intravaginal or Intracervical Insemination– not IUI.

Frozen Sperm

If you’re working with a known donor who lives far away or an unknown donor through a cryobank, you will likely be using a sample that has been collected in a clinic, washed to remove the semen, frozen, and stored at subzero temperature.

Benefits:

  • Frozen sperm has been examined under a microscope, and has been assessed for concentration, volume, and morphology (shape).

  • It’s easy to check sperm for other criteria that matters when you’re working towards conception, such as genetic variations that may be incompatible with your genetic predisposition.

Drawbacks:

  • It is substantially more expensive (in the short term, at least) to have a known donor’s sperm tested, washed, and frozen, when compared to a fresh sperm sample that hasn’t gone through any of those processes. It is also more expensive to buy sperm from a cryobank than it is to use sperm from a known donor.

  • It can be complicated to pick up frozen sperm and take it home or to a clinic (if it isn’t shipped there directly). The canister that sperm comes in is big and a tad ornery– it will fit in a normal-sized backpack but just barely.

Should we use a known or unknown donor?

There are benefits and drawbacks to both known and unknown donor options. To start, let’s define each:

Known Donor: A donor whose identity is known to you. A known donor is often someone you know, such as a friend or acquaintance, or can be someone you met for the express purpose of sperm donation.

Unknown Donor: A donor who went through an intermediary, whose identity is intended to be unknown to you. You may be familiar with the phrase “anonymous donor,” but because of readily available genetic testing, the concept of anyone being truly “anonymous” is no longer an option.

Now, what are the benefits and drawbacks of each type of donor? Let’s look!

Known Donor

Benefits:

  • Some families want the option of having a donor who is committing to some level of involvement in their lives (or the lives of their children). This option is only available if you use a known donor.

  • Should any questions about genetic diversity, allergies, developmental milestones, etc. come up, some families like the option of asking their donor for more information about those medical and/or developmental topics.

  • Some couples choose to have a relative donate sperm for their pregnancy, such as the brother of the partner who is not carrying the pregnancy. This allows for a genetic connection between the non-carrying partner and the pregnancy.

  • When working with a known donor, it is unlikely that they will have contributed to more than a handful of pregnancies throughout their lives, which is considered a positive by families who are concerned about the number of genetic “siblings” generated by one donor.

Drawbacks:

  • The legal connection between a known donor and a pregnancy can be complicated, depending on where you live. In some cases, known donors will have to go to court (perhaps even multiple times) in order to sever their legal connection to the pregnancy and ensuing baby. These court dates can be expensive.

  • There are times when donors have a change of heart, either about donating or about the type of relationship they would like to have with the pregnancy and ensuing baby. This can make for complicated, even legally messy situations.

  • In some cases, the relatives of the known donor may attempt to establish social or even legal connections to the pregnancy and/or ensuing baby.

Unknown Donor

Benefits:

  • Some families want the option of having a donor who has committed to no level of involvement in their lives (or the lives of their children). This guarantee is only available if you use an unknown donor.

  • If working with a cryobank, extensive testing is done on every donor with an emphasis on sperm quality/quantity, background examination of mental health conditions, and three generations of medical histories are examined for each donor.

  • If working with a cryobank, donors have already severed legal ties with their samples, so there is no concern about legal challenges by donors.

Drawbacks:

  • There are limited options for communicating with donors about medical questions or concerns. Cryobanks may be able to act as an intermediary, but the donor will be able to decide whether they choose to communicate and their anonymity will be prioritized throughout the process.

  • There are global limits placed on how many family units may be formed using any single donor’s sperm, and some cryobanks may choose to further limit the number of families created by their donors. However, it may still be possible that 15-25 families across the world have used the same donor you did, which means that your child/ren may have 60+ genetic “siblings.” While some families like having a connection to other families who used their donor, others don’t like the idea of having so many genetic relatives.

  • Some donor-conceived children believe that every person has the right to know the person who contributed the sperm that created them, and that type of relationship isn’t possible with an unknown donor.

Surrogacy

What is gestational surrogacy?

Gestational surrogacy is an arrangement in which a person carries a pregnancy for another person or couple. The gestational carrier undergoes the transfer of an embryo created through in vitro fertilization (IVF) using the egg and sperm of the intended parent(s) and/or a donor. The gestational carrier does not contribute eggs to the creation of the embryos and therefore is not genetically related to the child.

Who is surrogacy right for?

Gestational surrogacy is right for families who do not have a prospective parent with a uterus who is willing or able to carry a pregnancy to term.

Some examples:

  • A prospective parent has eggs from a fertility preservation, but is unable or does not want to carry a pregnancy.

  • Two partners both produce sperm and would like one them to be the genetic parent of their child.

How much does surrogacy cost?

There are many contributing factors that affect the cost of surrogacy, including:

  • Using a known surrogate or an agency

  • Using your own genetic material or a donor

  • Care and complications such as multiple IVF cycles and twins

  • Legal challenges concerning parental rights

We provide you the resources to understand the total expected costs involved in your surrogacy journey and reliable experts to guide you throughout.

What are my surrogacy options?

You will make many choices when it comes to gestational surrogacy, but the first you must make are whether to use a known surrogate or a surrogacy agency.

A known surrogate can be a friend, family member, acquaintance and is also known as an altruistic surrogate.

A compensated surrogate is a surrogate you will be connected through via a surrogacy agency. The agencies we work with are sensitive to each family’s unique needs, and will find you a surrogate who is excited to help you have a child.

What legal considerations should I be aware of?

A surrogacy attorney can help you navigate all of the legal considerations that are unique to your circumstances. In the state of Pennsylvania, compensated gestational surrogacy is legal, and up to two parents can get a pre-birth order to be listed on the birth certificate, regardless of their gender, marital status, or genetic connection to the child. However, courts in individual counties can exercise a challenge to these legal rights, which may take several court visits to resolve.

Directed Donations

What are directed donations?

If you’ve been invited to give sperm or eggs to a family trying to conceive, Main Line Fertility is here to support you through every step of the directed donation process.

Who are directed donations right for?

If you are an individual under the age of 40, without any known fertility challenges, and you know a family who is trying to conceive, you may want to give a directed donation to help that family on their fertility journey.

Giving your genetic material is an altruistic gift; however, it is important that you and the family who you will be donating to have agreed upon the expectations for your relationship and any relationship to the child. You should also be prepared to deal with a sometimes frustrating court system when you are relinquishing your legal rights to any child born with your genetic material.

What is the process like for sperm donation?

Before you provide your sample, you must refrain from any sexual activity including masturbation for 2 to 3 days prior to donation. (Longer or shorter periods of abstinence may result in abnormal results.)

You will give your sperm sample at Main Line for via masturbation on-site in our laboratory collection room. The room is equipped with a chair/bed, urinal, sink, and TV/VCR. A limited collection of sexually explicit material is provided in the collection room, or you are welcome to use your own smartphone. (Note: No lubricants or condoms are allowed.)

When you’ve given your sample, you’ll get a complete semen work-up includes concentration (recorded in millions per milliliter), motility (to determine how many sperm are moving in the sample), and morphology (% of normally shaped sperm).

Your sperm will either be used immediately for a fertility procedure or cryopreserved (frozen) for future use.

What is the process like for egg donation?

If you are donating eggs for immediate use, you will work with Main Line Fertility to coordinate your cycle with the cycle of the person who will be carrying the pregnancy.

Over a period of 9-12 days, we will stimulate your ovaries with self-administered injections. These injections utilize a thin needle (similar to what a diabetic might use for insulin shots) and are given subcutaneously, which means below the skin (as opposed to in the muscle). You will also have approximately five to seven early morning monitoring appointments to assess whether the injections are working.

Once the monitoring shows that the egg maturing process has worked, you will come to our on-site surgery center where your doctor will gently guide a needle attached to a catheter through your vaginal wall to collect your eggs. The painless procedure will take 10-20 minutes and you will be under twilight anesthesia. Most patients don’t even remember the procedure, and you may bring a partner or friend with you if you’d like. There are no stitches or scars and most patients return to work the following day.

Your eggs will then be combined with sperm to create the embryos that will either be inserted into the person carrying the pregnancy or cryopreserved for a future pregnancy.

How much do directed donations cost?

For a family trying to conceive, directed donations (i.e. using a known donor) can save them money over purchasing eggs or sperm from a cryobank. However, the family is still responsible for all of the costs of extraction, testing, and storage of genetic material. The family is also responsible for any legal fees that may be incurred as part of the process of obtaining their legal rights as parents.